Genetic variants associated with deep vein thrombosis: theF11locus

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Gene variants associated with deep vein thrombosis.

CONTEXT The genetic causes of deep vein thrombosis (DVT) are not fully understood. OBJECTIVE To identify single-nucleotide polymorphisms (SNPs) associated with DVT. DESIGN, SETTING, AND PATIENTS We used 3 case-control studies of first DVT. A total of 19 682 gene-centric SNPs were genotyped in 443 cases and 453 controls from the Leiden Thrombophilia Study (LETS, 1988-1992). Twelve hundred si...

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Updated analysis of gene variants associated with deep vein thrombosis.

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Over the past 10 years more than 700 cases of brucellosis have been reported in Kosovo, which is heavily oriented towards agriculture and animal husbandry. Here, brucellosis is still endemic and represents an uncontrolled public health problem. Human brucellosis may present with a broad spectrum of clinical manifestations; among them, vascular complications are uncommon. Hereby we describe the ...

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BACKGROUND Hemorrhagic manifestations are common with Dengue but thrombotic events are uncommonly reported. CASE CHARACTERISTICS 11-year-old boy who presented with ileo-femoral deep vein thrombosis associated with serologically confirmed infection with DEN1 dengue virus. OBSERVATION There was no other history or investigation suggestive of a procoagulant state. OUTCOME Successfully treate...

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ژورنال

عنوان ژورنال: Journal of Thrombosis and Haemostasis

سال: 2009

ISSN: 1538-7933,1538-7836

DOI: 10.1111/j.1538-7836.2009.03544.x